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2016 Fiscal Year Final Research Report

Gene mutation analysis of esophageal cancer in the era of post genome-sequense

Research Project

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Project/Area Number 26461986
Research Category

Grant-in-Aid for Scientific Research (C)

Allocation TypeMulti-year Fund
Section一般
Research Field Digestive surgery
Research InstitutionNagoya City University

Principal Investigator

KIMURA Masahiro  名古屋市立大学, 大学院医学研究科, 研究員 (50336682)

Project Period (FY) 2014-04-01 – 2017-03-31
Keywords次世代シークエンス / 食道癌
Outline of Final Research Achievements

Next generataion Sequence was done about 400 genes using Truseq Custum Trial kit (Cancer Gene) for 48 samples of esophageal cancer. We found the mutaion of 7 genes involved T factor (AKAP9, ATM, CYTSB, DDX10, MYH7, MYST4 and PRDM16) Moreover, we found 8 gene mutaion involved N factor (BCR, CARD11, FANCA, JAZF1, NIN, NSD1, RAMBP17 and REQL4).
This result of analysis for these 400 genes were similar to 30,000 genes of whole genomic analysis in other facilities.

Free Research Field

医歯薬学

URL: 

Published: 2018-03-22  

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