2016 Fiscal Year Final Research Report
Inhibition of Eph receptor A4 by 2,5-dimethylpyrrolyl benzoic acid suppresses human pancreatic cancer growing orthotopically in nude mice
| Project/Area Number |
26462052
|
|---|
| Research Category |
Grant-in-Aid for Scientific Research (C)
|
| Allocation Type | Multi-year Fund |
|---|
| Section | 一般 |
|---|
| Research Field |
Digestive surgery
|
|---|
| Research Institution | Hokkaido University |
|---|
Principal Investigator |
|
|---|
| Project Period (FY) |
2014-04-01 – 2017-03-31
|
| Keywords | Ephrin receptor A4 / 分子標的治療 / 膵癌 |
|---|
| Outline of Final Research Achievements |
Our study indicated that EphA4 expression was an independent prognostic factor in pancreatic cancer. Our study indicated that 2,5-dimethylpyrrolyl benzoic acid showed a cytostatic efficacy in pancreatic cancer expressing EphA4 in vitro and in vivo.
|
| Free Research Field |
膵癌新規治療の開発
|
