Efficacy of neoadjuvant chemoradiotherapy for pancreatic ductal adenocarcinoma

2017 Fiscal Year Final Research Report

• Project/Area Number: 26462068
• Research Category: Grant-in-Aid for Scientific Research (C)
• Allocation Type: Multi-year Fund
• Section: 一般
• Research Field: Digestive surgery
• Research Institution: Kagoshima University
• Principal Investigator: Shinchi Hiroyuki 鹿児島大学, 医歯学域医学系, 教授 (60284874)
• Co-Investigator(Kenkyū-buntansha): 又木 雄弘 鹿児島大学, 医歯学域附属病院, 特任講師 (10444902) ; 前村 公成 鹿児島大学, 医学部・歯学部附属病院, 助手 (30398292) ; 夏越 祥次 鹿児島大学, 医歯学域医学系, 教授 (70237577) ; 蔵原 弘 鹿児島大学, 医学部・歯学部附属病院, その他 (70464469)
• Project Period (FY): 2014-04-01 – 2018-03-31
• Keywords: 膵癌 / 化学放射線療法 / 術前治療 / 外科治療

Outline of Final Research Achievements

We have examined the efficacy of neoadjuvant chemoradiotherapy (NACRT) for pancreatic ductal adenocarcinoma (PDAC). This study included 17 patients who underwent upfront surgery, 11 patients with surgical resection after NACRT, and 22 patients w/o resection after NACRT, respectively. The median survival time (MST) of patients with surgical resection after NACRT was significantly better than other groups.

Free Research Field

消化器外科学