Vascularized Lymph-node Transfer for Lymphedema Patients

2017 Fiscal Year Final Research Report

• Project/Area Number: 26462115
• Research Category: Grant-in-Aid for Scientific Research (C)
• Allocation Type: Multi-year Fund
• Section: 一般
• Research Field: Cardiovascular surgery
• Research Institution: Yokohama City University
• Principal Investigator: Satake Toshihiko 横浜市立大学, 附属市民総合医療センター, 准教授 (60271318)
• Co-Investigator(Kenkyū-buntansha): 安村 和則 横浜市立大学, 大学病院, 助手 (40351621)
• Project Period (FY): 2014-04-01 – 2018-03-31
• Keywords: リンパ浮腫 / 血管柄付き皮弁 / リンパ節移植

Outline of Final Research Achievements

One of the purposes of this study is to investigate therapeutic effects of vascularized lymph-node transfer with lympho-vessel regenerative factors for lymphedema patients. We could make acute upper and lower extremities lymphedema experimental model using the small animal, such as SD rats. However lymphedema was spontaneously relieved within two to three weeks, moreover we could not maintain chronic lymphedema even after the irradiation therapy. On the other hand, we could developed vascularized inguinal or axillary lymph-node transfer model for chronic lymphedema using the SD rats.

Free Research Field

形成外科学