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2016 Fiscal Year Final Research Report

Functional connectivy after operation for spinal cord injury

Research Project

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Project/Area Number 26462205
Research Category

Grant-in-Aid for Scientific Research (C)

Allocation TypeMulti-year Fund
Section一般
Research Field Neurosurgery
Research InstitutionOsaka University

Principal Investigator

Ishihara Masahiro  大阪大学, 医学系研究科, 特任研究員 (00533803)

Project Period (FY) 2014-04-01 – 2017-03-31
Keywords神経再生 / 脊髄損傷 / 嗅粘膜 / fMRI
Outline of Final Research Achievements

We performed olfactory mucosa transplantation to 5 patients of complete spinal cord injury. 4 patients showed lower extremity functional recovery. Functional MRI was performed before and after operation. Functional MRI showed activation of left precentral gyrus and right cerebellum. In contrast, activation at left postcentral gyrus, left parahippocampal gyrus and left globus pallidus was decreased. We detected alteration of brain activity by lower extremity recovery after olfactory mucosa transplantation.

Free Research Field

神経再生

URL: 

Published: 2018-03-22  

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