Functional connectivy after operation for spinal cord injury

2016 Fiscal Year Final Research Report

• Project/Area Number: 26462205
• Research Category: Grant-in-Aid for Scientific Research (C)
• Allocation Type: Multi-year Fund
• Section: 一般
• Research Field: Neurosurgery
• Research Institution: Osaka University
• Principal Investigator: Ishihara Masahiro 大阪大学, 医学系研究科, 特任研究員 (00533803)
• Project Period (FY): 2014-04-01 – 2017-03-31
• Keywords: 神経再生 / 脊髄損傷 / 嗅粘膜 / ｆMRI

Outline of Final Research Achievements

We performed olfactory mucosa transplantation to 5 patients of complete spinal cord injury. 4 patients showed lower extremity functional recovery. Functional MRI was performed before and after operation. Functional MRI showed activation of left precentral gyrus and right cerebellum. In contrast, activation at left postcentral gyrus, left parahippocampal gyrus and left globus pallidus was decreased. We detected alteration of brain activity by lower extremity recovery after olfactory mucosa transplantation.

Free Research Field

神経再生