2016 Fiscal Year Final Research Report
Development of diagnostic and predictive tool for motor function decline focusing on sarcopenia and spinal alignment change
| Project/Area Number |
26462249
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| Research Category |
Grant-in-Aid for Scientific Research (C)
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| Allocation Type | Multi-year Fund |
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| Section | 一般 |
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| Research Field |
Orthopaedic surgery
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| Research Institution | Wakayama Medical University |
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Principal Investigator |
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| Research Collaborator |
TERAGUCHI Masatoshi
IWAHASHI Hiroki
SASAKI Takahide
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| Project Period (FY) |
2014-04-01 – 2017-03-31
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| Keywords | 脊椎 / 加齢変性 / 傍脊柱筋 / 大腰筋 / 腰痛 / 矢状面バランス / 一般住民 / MRI |
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| Outline of Final Research Achievements |
A forward shift of the sagittal vertical axis is reported to be a radiographic predictor of low back pain as well as disability of ADL in elderly. The purpose of this study was to elucidate the association of degenerative changes on MRI and sagittal imbalace in a general population. A total of 794 inhabitants were subjected to a sagittal radiograph of the whole spine in a standing position and whole spine MRI. Cross-sectional area (cm2) and percentage of the fatty degeneration area in the spinal muscles were measured by a DICOM software. Mean cross-sectional areas of the muscles around the lumbar spine were significantly reduced with elevation of age strata in both genders. The fatty degeneration was significantly predominant in the paravertebral muscles in compared to the psoas muscles in both genders. The spinal imbalance was significantly associated with low back pain. Degeneration of the paravertebral muscle at L1 level was a significant associated factor of sagittal imbalance.
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| Free Research Field |
整形外科学
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