2016 Fiscal Year Final Research Report
Establishment of the double-contrast agent -an effort to detect the rabbit knee cartilage degeneration in the early stage-
| Project/Area Number |
26462311
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| Research Category |
Grant-in-Aid for Scientific Research (C)
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| Allocation Type | Multi-year Fund |
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| Section | 一般 |
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| Research Field |
Orthopaedic surgery
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| Research Institution | Kyoto Prefectural University of Medicine |
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Principal Investigator |
Ikoma Kazuya 京都府立医科大学, 医学(系)研究科(研究院), 講師 (50516044)
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| Research Collaborator |
KIDO Masamitsu
ONISHI Okkihiro
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| Project Period (FY) |
2014-04-01 – 2017-03-31
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| Keywords | 整形外科学 / MRI |
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| Outline of Final Research Achievements |
MRI is used recently to assess the degeneration of articular cartilage. However articular cartilage is a thin layer and has same signal intensity as the joint fluid, so it is difficult to distinguish between the articular cartilage and the adjacent joint fluid on MR images. To depict the articular cartilage, we obtained MR images after injecting a contrast agent with manganese ion. The agent depressed the signal intensity of the joint fluid, which made a contrast between the articular cartilage and the joint fluid. This new method enabled us to visualize the articular cartilage more vividly and in the earlier stage than the conventional method.
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| Free Research Field |
外科学
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