2016 Fiscal Year Final Research Report
Comprehensive analysis of cytokine and chemokine in prostatic hypertrophy with non-bacterial chronic inflammation
| Project/Area Number |
26462444
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| Research Category |
Grant-in-Aid for Scientific Research (C)
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| Allocation Type | Multi-year Fund |
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| Section | 一般 |
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| Research Field |
Urology
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| Research Institution | Kagawa University |
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Principal Investigator |
Sugimoto Mikio 香川大学, 医学部附属病院, 准教授 (10243768)
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| Project Period (FY) |
2014-04-01 – 2017-03-31
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| Keywords | 前立腺炎 / サイトカイン / ケモカイン |
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| Outline of Final Research Achievements |
We elucidated that some chemokines, including CCL2/MCP-1 and CXCL1/CINC-1, were elevated in the prostate and urine of non-bacterial prostatitis(NBP) model rats, and Eviprostat potently suppressed the increases in CCL2/MCP-1 and CXCL1/CINC-1. These chemokines are therefore candidate diagnostic biomarkers for nonbacterial chronic prostatic inflammation. However, in human urine, we could not detect the change of chemokines. Further study for detection in human urine is warranted.
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| Free Research Field |
泌尿器科学
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