2016 Fiscal Year Final Research Report
p38 enhances middle ear proliferation during bacterial otitis media
| Project/Area Number |
26462566
|
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| Research Category |
Grant-in-Aid for Scientific Research (C)
|
| Allocation Type | Multi-year Fund |
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| Section | 一般 |
|---|
| Research Field |
Otorhinolaryngology
|
|---|
| Research Institution | Juntendo University |
|---|
Principal Investigator |
|
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| Project Period (FY) |
2014-04-01 – 2017-03-31
|
| Keywords | 急性中耳炎 / 中耳粘膜肥厚 / ｐ３８ / 分子制御 |
|---|
| Outline of Final Research Achievements |
The irreversible hypertrophy of the middle ear mucosa was occurred in chronic otitis media and adhesive otitis media. The molecular mechanism of mucosal hypertrophy by p38 in middle ear was clarified. The new treatmnt of hypertrophy of the middle ear mucosa by p38 antagonist was suggested.
|
| Free Research Field |
耳鼻咽喉科学
|
