2016 Fiscal Year Final Research Report
Pathogenesis of myopic glaucoma and OCT program for it.
| Project/Area Number |
26462632
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| Research Category |
Grant-in-Aid for Scientific Research (C)
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| Allocation Type | Multi-year Fund |
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| Section | 一般 |
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| Research Field |
Ophthalmology
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| Research Institution | Kanazawa University |
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Principal Investigator |
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| Co-Investigator(Renkei-kenkyūsha) |
HIGASHIDE Tomomi 金沢大学, 附属病院, 講師 (20291370)
OHKUBO Shinji 金沢大学, 医学系, 協力研究員 (90362003)
NITTA kouji 金沢大学, 医学系, 協力研究員 (10260556)
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| Project Period (FY) |
2014-04-01 – 2017-03-31
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| Keywords | myopic glaucoma / disc hemorrhage / open angle glaucoma / glaucoma progresshion / high myopia |
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| Outline of Final Research Achievements |
We clarify differences between highly myopic and non-myopic primary open-angle glaucoma (POAG) patients, including normal-tension glaucoma patients.
We analyzed 53 highly myopic and 93 non-myopic POAG patients. The cumulative probability of non-progression of visual field (VF) loss was significantly greater in the highly myopic group than in the non-myopic group (P=0.0142). The occurrence of disc hemorrhage (DH) of the non-myopic group was significantly greater than the highly myopic group (P=0.0311). The cumulative probability of DH was significantly greater in the non-myopic group than in the highly myopic group (P=0.0413).Highly myopic POAG is considered a combination of myopic optic neuropathy （MON) and glaucomatous optic neuropathy (GON). If GON is predominant, it has frequent DH and more progressive VF loss. However, when the MON is predominant, it has less DH, and less progressive VF loss.
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| Free Research Field |
医歯薬学
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