2016 Fiscal Year Final Research Report
Histological study for structural aspects and stimulus conducting function in the supratarsal Mueller's muscle of the eyelid
| Project/Area Number |
26462727
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| Research Category |
Grant-in-Aid for Scientific Research (C)
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| Allocation Type | Multi-year Fund |
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| Section | 一般 |
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| Research Field |
Plastic surgery
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| Research Institution | Shinshu University |
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Principal Investigator |
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| Project Period (FY) |
2014-04-01 – 2017-03-31
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| Keywords | 眼瞼 / ミュラー筋 / アドレナリン受容体 / 交感神経 / 眼瞼下垂症 / 眼瞼内反症 / ビメンチン |
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| Outline of Final Research Achievements |
Mueller's muscle is a smooth muscle tissue on the margin of eyelid. It is contracted by stimulation of the sympathetic nerve. It is not only one of the muscle elevating upper eyelid but also a mechanoreceptor in order to contract the levator palpebral muscle which is a main eye opening skeletal muscle innervated by oculomotor nerve. In this histological study, we found that Mueller’s muscle was composed of smooth muscles originated from mesoderm like blood vessels and urinary bladder, and that there were some types of gap junctions between the smooth muscles. Some types of adrenergic receptors except beta 2 were found in the smooth muscle tissues in the order of beta 1, alpha 2, alpha 1.
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| Free Research Field |
形成外科学
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