2016 Fiscal Year Final Research Report
Use of quaternary ammonium methacrylate to improve the long-term stability of composite resin restorations
| Project/Area Number |
26462895
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| Research Category |
Grant-in-Aid for Scientific Research (C)
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| Allocation Type | Multi-year Fund |
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| Section | 一般 |
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| Research Field |
Conservative dentistry
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| Research Institution | Nihon University |
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Principal Investigator |
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| Project Period (FY) |
2014-04-01 – 2017-03-31
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| Keywords | コンポジットレジン / ボンディング / MMA / QAM / 接着試験 |
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| Outline of Final Research Achievements |
Polymerizable quaternary ammonium methacrylate (QAM), which suppresses matrix metalloproteinase (MMA), was added to a bonding material to improve the long-term stability of composite resin restorations. This study was approved by the ethics committee of our university. Two types of QAM;METMAC and MCMS were synthesized and used at a final concentration of 10%. Dentin-resin bonded specimens (control, METMAC, and MCMS; each n = 10) were prepared and stored in water for 24 h. Then, a bonding strength test was conducted at a crosshead speed of 1 mm/min. Significant differences in bonding strength were found between the control and METMAC or MCMS, but they all satisfied the minimum required bonding strength. In contrast with these results, the results of a bonding strength test conducted after storage in water for 1 year revealed significant differences in bonding strength among the control, METMAC, and MCMS as well as inhibition of MMA by METMAC and MCMS.
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| Free Research Field |
保存修復学
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