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2016 Fiscal Year Final Research Report

Guideline for the early diagnosis of residual ridge by using NaF-PET/CT and FEA

Research Project

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Project/Area Number 26462912
Research Category

Grant-in-Aid for Scientific Research (C)

Allocation TypeMulti-year Fund
Section一般
Research Field Prosthodontics/ Dental materials science and
Research InstitutionTohoku University

Principal Investigator

SUENAGA HANAKO  東北大学, 歯学研究科, 助教 (00508939)

Research Collaborator YAMAGUCHI KEIICHIRO  東北大学, サイクロトロンラジオアイソトープセンター, 研究教授
Li Qing  The University of Sydney, Aerospace, Mechanical and Mechatronics Engineering, Professor
Swain Mike  The University of Kuwait, Faculty of Dentistry, Professor
Project Period (FY) 2014-04-01 – 2017-03-31
Keywordsメカノバイオロジー / 骨代謝 / NaF-PET / FEA
Outline of Final Research Achievements

NaF Positron Emission Tomography (PET) can identify subtle functional variation prior to the major structural change detectable by X-ray. NaF-PET/CT scan was performed to examine the change of bone metabolism in the residual ridge underneath denture before and after the RPD treatment. The resultant mechanobiological response was analyzed using a 3D finite element (FE) model derived from the computerized tomography (CT) images of a corresponding patient under the occlusal loading. Mechanobiological stimulus determined from the FEA are quantified and compared with the standardized uptake values (SUV) of PET.
The increased application of occlusal force after RPD insertion induced higher mechanical stimuli in the residual bone, and SUV increased in the region of residual ridge with higher mechanical stimuli. SUV had clear correlation with mechanical stimulus in the cancellous bone, especially after RPD insertion (R2 > 0.8, p < 0.01).

Free Research Field

歯科補綴学

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Published: 2018-03-22  

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