2016 Fiscal Year Final Research Report
Investigation The relationship between oral function and general health with Twin study
| Project/Area Number |
26462918
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| Research Category |
Grant-in-Aid for Scientific Research (C)
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| Allocation Type | Multi-year Fund |
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| Section | 一般 |
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| Research Field |
Prosthodontics/ Dental materials science and
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| Research Institution | Osaka University |
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Principal Investigator |
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| Co-Investigator(Renkei-kenkyūsha) |
IKEBE KAZUNORI 大阪大学, 大学院歯学研究科, 准教授 (70273696)
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| Project Period (FY) |
2014-04-01 – 2017-03-31
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| Keywords | 双子研究 / 口腔機能 |
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| Outline of Final Research Achievements |
This study was conducted to quantify the genetic and environmental contributions to oral disease and function in twins. Number of teeth, percentage of decayed, filled and missing teeth and periodontal status were recorded. Furthermore, stimulated salivary flow rate,occlusal force and masticatory performance were measured. Univariate genetic analysis with monozygotic and dizygotic twin pairs was conducted to detect the fittest structural equation model of each outcome. Both number of teeth and periodontal status fitted the model composed of common environmental factor and unique environmental factor. Decayed, filled and missing teeth, morphological figures and measurements of oral function fitted the model composed of additive genetic factor and unique environmental factor. The model fitting of each measurement suggested that periodontal disease was mainly affected by environmental factors, while oral functions were influenced by both genetic and environmental factors.
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| Free Research Field |
歯科補綴学
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