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2016 Fiscal Year Final Research Report

Mechanical and histrogical analysis bone to implant contact in type2 diabetes rats model with antidiabetic drugs.

Research Project

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Project/Area Number 26462931
Research Category

Grant-in-Aid for Scientific Research (C)

Allocation TypeMulti-year Fund
Section一般
Research Field Prosthodontics/ Dental materials science and
Research InstitutionKagoshima University

Principal Investigator

Kawamoto Shinichiro  鹿児島大学, 医歯学総合研究科, 客員研究員 (70295260)

Project Period (FY) 2014-04-01 – 2017-03-31
Keywordsインプラント / 糖尿病
Outline of Final Research Achievements

Diabetes mellitus is one of the relative contraindication in dental implant treatment. But the effect of bone-implant contact is unknown. So we investivated bone-inplant contact. In vitro, we found that alkaline phosphatase activety is lower in high gllucose conditioned medium than that of normal conditioned medium. In vivo study, we evaluated bone-implant contact between type 1 diabetes mellitus rats with or without antidiabetic drugs. There are no differention between two group in bone-implant contact.

Free Research Field

歯科補綴学

URL: 

Published: 2018-03-22  

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