2016 Fiscal Year Final Research Report
Tissue engineering using injectable bone substitute material with gene transfer
Project/Area Number |
26462932
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Research Category |
Grant-in-Aid for Scientific Research (C)
|
Allocation Type | Multi-year Fund |
Section | 一般 |
Research Field |
Prosthodontics/ Dental materials science and
|
Research Institution | Iwate Medical University |
Principal Investigator |
|
Project Period (FY) |
2014-04-01 – 2017-03-31
|
Keywords | 組織再生 / 骨組織 / バイオマテリアル |
Outline of Final Research Achievements |
The aim of this study was to investigate osteogenic differentiation profiles on nano haydoroxi apatite and hyaluronic acid composite(nHAP/HLA) with osteoblast deifferentiation factors, such as BMP-2.Injectable nHAP/HLA was produced and implanted on mouse calbariae without incision. This newly developed nano biomaterial was formed in 37 degree environment and create the additional space for bone induction between bone and periosteum.Ectopic bone formation was observed on calvarial tisuue after injection of nHAP/HLA with BMP2.
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Free Research Field |
補綴歯科学
|