Analyzed stem cell differentiation and regeneration property treated by non steroidal anti-inflammatory agent

2016 Fiscal Year Final Research Report

• Project/Area Number: 26462981
• Research Category: Grant-in-Aid for Scientific Research (C)
• Allocation Type: Multi-year Fund
• Section: 一般
• Research Field: Dental engineering/Regenerative dentistry
• Research Institution: The Nippon Dental University
• Principal Investigator: Tsutsui Takeo 日本歯科大学, 生命歯学部, 教授 (70366764)
• Project Period (FY): 2014-04-01 – 2017-03-31
• Keywords: 歯髄幹細胞 / 歯根膜細胞 / 非ステロイド性抗炎症薬 / アスピリン / NSAIDs / 幹細胞 / 分化誘導

Outline of Final Research Achievements

We analyzed stem cell property that treated with non steroidal anti-inflammatory agent (NSAIDs) using mouse dental pulp cells, human dental pulp stem cells and human periodontal ligament cells. Differentiation potential analyzed by treated with high dose or low dose aspirin. Cultured in osteogenic and adipogenic differentiation medium, prompt positive staining reveled in treated with high dose aspirin. When cultured in adipogenic medium, prompt positive staining reveled in treated with high dose aspirin.

Free Research Field

幹細胞