bone regneration technique wit non-cultured mono nuclear cell derived from peripheral blood

2016 Fiscal Year Final Research Report

• Project/Area Number: 26463061
• Research Category: Grant-in-Aid for Scientific Research (C)
• Allocation Type: Multi-year Fund
• Section: 一般
• Research Field: Surgical dentistry
• Research Institution: Nagasaki University
• Principal Investigator: OHBA Seigo 長崎大学, 病院(歯学系), 講師 (80363456)
• Research Collaborator: SANO Kazuo ; ASAHINA Izumi ; Blake Roessler J
• Project Period (FY): 2014-04-01 – 2017-03-31
• Keywords: 骨再生 / PRP / hydroxyapatite/collagen

Outline of Final Research Achievements

Bone regeneration was induced by hydroxyapatite/collagen composite material (HAp/Col) as a carrer and non-cultured total peripheral blood. HAp/Col with peripheral blood (PB group) or normal salin (NS group) were implanted on the calvarium of nude mice. The mature bone regeneration was observed 8 postoperative weeks in PB group. The volume of new bone was significantly much in PB group. In rabbits, HAp/col or HAp were filled into the maxillary sinus with peripheral blood. New bone was more induced in HAp/Col group same as mouse.
According to these results, HAp/Col with peripheral blood is considered to be useful for bone regeneration.

Free Research Field

外科系歯学