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2016 Fiscal Year Final Research Report

The relationship between improvement of periodontal tissue and blood leptin, brain activation by periodontal initial treatment

Research Project

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Project/Area Number 26463140
Research Category

Grant-in-Aid for Scientific Research (C)

Allocation TypeMulti-year Fund
Section一般
Research Field Periodontology
Research InstitutionKyushu Dental College

Principal Investigator

Muraoka Kosuke  九州歯科大学, 歯学部, 講師 (80382422)

Project Period (FY) 2014-04-01 – 2017-03-31
Keywords歯周基本治療 / fMRI / 血中レプチン / 脳
Outline of Final Research Achievements

The aim of this study is to examine whether improvement of periodontal tissue affects changes in blood leptin and brain activity in chronic periodontitis patients. Periodontal initial treatment was showed significant improvement of periodontal tissue, and the activity of higher brain functions were confirmed in fMRI imaging. Chronic periodontitis was caused unpleasant irritation, and chronic periodontitis was inhibited work memory and higher brain function. However, periodontal initial treatment was removed unpleasant irritation and brain activation recovered.

Free Research Field

歯周疾患

URL: 

Published: 2018-03-22  

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