2016 Fiscal Year Final Research Report
Establishment of the novel oral health care guidelines based on oral microbiome analysis
| Project/Area Number |
26463165
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| Research Category |
Grant-in-Aid for Scientific Research (C)
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| Allocation Type | Multi-year Fund |
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| Section | 一般 |
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| Research Field |
Social dentistry
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| Research Institution | Kyushu University |
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Principal Investigator |
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| Project Period (FY) |
2014-04-01 – 2017-03-31
|
| Keywords | 唾液 / 細菌叢 / 舌苔 / プラーク / 歯周病 |
|---|
| Outline of Final Research Achievements |
Saliva (SL), tongue coating (TC), supragingival plaque (AP), and subgingival plaque (BP) samples were collected twice from 14 patients with periodontitis who visited a dental clinic at their initial visit (pre-therapy samples) and after periodontal therapy (post-therapy samples). A principal coordinate analysis (PCoA) plot demonstrated that SL microbiota was distinct from both BP and AP microbiota, but closely similar to TC microbiota both pre- and post-therapy. Temporal variation following therapy in the SL and TC bacterial population was significantly smaller than in the AP microbiota, and relative abundances of the predominant bacterial species changed similarly in the SL and TC microbiota. These results suggested that the SL microbiota might originate from the TC microbiota.
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| Free Research Field |
予防歯科
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