Does obesity cause lymphedema?- Diversified approaches to adipose tissue and lymph vessels

2016 Fiscal Year Final Research Report

• Project/Area Number: 26463215
• Research Category: Grant-in-Aid for Scientific Research (C)
• Allocation Type: Multi-year Fund
• Section: 一般
• Research Field: Fundamental nursing
• Research Institution: Nagoya University
• Principal Investigator: Takeno Yukari 名古屋大学, 医学系研究科(保健), 助教 (20509088)
• Project Period (FY): 2014-04-01 – 2017-03-31
• Keywords: リンパ浮腫 / 肥満 / 糖尿病 / ラット / リンパ速度 / インドシアニングリーン / 免疫組織化学

Outline of Final Research Achievements

The purpose of the present study was to explore the relationship between obesity and lymphedema and then develop lymphedema care and the management.
Animal experiment, using obese rats and diabetes rats, was employed in measurement of lymph velocity, excretion time of labeled interstitial fluid, and lymph vessels and adipose tissue were examined by immunohistochemical study. These finding suggest that interstitial fluid is more likely to accumulate in the obese body than normal. Moreover, the lower level of leptin hormone and the heavier weight in lymphedema rats could cause uninhibited appetite and further weight gain. Based on the findings, we plan to develop lymphedema management.

Free Research Field

基礎看護学