Development of the countermeasure for musculoskeletal atrophy in outer space

2016 Fiscal Year Final Research Report

• Project/Area Number: 26506025
• Research Category: Grant-in-Aid for Scientific Research (C)
• Allocation Type: Multi-year Fund
• Section: 一般
• Research Field: 宇宙生命学
• Research Institution: Kurume University
• Principal Investigator: Shiba Naoto 久留米大学, 医学部, 教授 (20187389)
• Research Collaborator: Matsuse Hiroo ; Hashida Ryuki ; Omoto Masayuki ; Yamamoto Naosuke
• Project Period (FY): 2014-04-01 – 2017-03-31
• Keywords: 廃用予防 / 筋力増強運動 / エルゴメータ / 有酸素運動 / 宇宙医学

Outline of Final Research Achievements

Hybrid training System (HTS) is to create resistance to the motion of a volitionally contracting agonist muscle by means of the force generated by its electrical stimulated eccentric antagonist muscle. We developed the new training method that HTS is combined with a cycle ergometer (HCE). HCE stimulated acute increases in growth hormone, lactate and IL-6 than conventional ergometer at the same workload. Moreover, HCE improved the peak oxygen uptake and knee muscle strength with the training program used in orbit (30-min HCE at a 3-time session a week for 6 weeks ). The change of knee extension strength by HCE was greater than by a ergometer exercise without HTS. We simulated that HCE effectively increased the oxygen uptake in a linear manner, and additional stimulation of muscles at the ankle joint increased the oxygen uptake. In the flight experiment, we confirmed that HCE was performed without a problem. HCE seems to be a useful method in orbit or space flight.

Free Research Field

筋骨格系廃用予防