2016 Fiscal Year Final Research Report
Structural ans functional analysis of single-stranded DNA-binding protein DdrA
| Project/Area Number |
26506030
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| Research Category |
Grant-in-Aid for Scientific Research (C)
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| Allocation Type | Multi-year Fund |
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| Section | 一般 |
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| Research Field |
宇宙生命学
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| Research Institution | Japan Aerospace EXploration Agency |
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Principal Investigator |
YAMADA Mitsugu 国立研究開発法人宇宙航空研究開発機構, 有人宇宙技術部門, 主任研究開発員 (80510924)
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| Project Period (FY) |
2014-04-01 – 2017-03-31
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| Keywords | タンパク質結晶解析 / 構造生物学 |
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| Outline of Final Research Achievements |
In this study, crystallizaion experiments were cariied out to obtain the information of structural and functional relationship of DdrA, a DNA-related protein repair-related protein of Deinococcus radiodurans.
We have constructed expression vector of DdrA derived from multiple species and successfully selected the constructs suitable for crystallization. We also found that there is novel processing mechanism.
We are going to clarify the new processing mechanism as well as advance the crystal analysis in the future.
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| Free Research Field |
構造生物学
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