2016 Fiscal Year Final Research Report
Study on the network of longevity control genes expressed under space environments
| Project/Area Number |
26506033
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| Research Category |
Grant-in-Aid for Scientific Research (C)
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| Allocation Type | Multi-year Fund |
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| Section | 一般 |
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| Research Field |
宇宙生命学
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| Research Institution | Waseda University (2016)
Tokyo Metropolitan Geriatric Hospital and Institute of Gerontology (2014-2015) |
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Principal Investigator |
Honda Shuji 早稲田大学, 理工学術院総合研究所(理工学研究所), その他(招聘研究員) (40100127)
|
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| Project Period (FY) |
2014-04-01 – 2017-03-31
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| Keywords | 宇宙 / 線虫 / 老化 / 重力 |
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| Outline of Final Research Achievements |
Space environments down regulate the expression of more than ten neuronal genes in the nematode Caenorhabditis elegans. We investigated the involvement of these genes in aging and gravity. We examined the effects of aging, mutation in daf-16, the downstream of insulin/IGF signaling, and hypergravity: 100G. These genes responded in various ways to aging, insulin/IGF signaling and hypergravity.
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| Free Research Field |
基礎老化学
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