A mathematical model of the jigsaw puzzle appearance of Arabidopsis leaf pavement cells

2016 Fiscal Year Final Research Report

• Project/Area Number: 26520207
• Research Category: Grant-in-Aid for Scientific Research (C)
• Allocation Type: Multi-year Fund
• Section: 特設分野
• Research Field: Mathematical Sciences in Search of New Cooperation
• Research Institution: Kyushu University
• Principal Investigator: Takigawa-Imamura Hisako (滝川寿子) 九州大学, 医学研究院, 助教 (30523790)
• Co-Investigator(Renkei-kenkyūsha): KUTSUNA Natsumaro 東京大学, 大学院新領域創成科学研究科, 特任准教授 (70578559) ; KOBARASHI Ryo 広島大学, 大学院理学研究科, 教授 (60153657) ; MIURA Takashi 九州大学, 大学院医学研究院, 教授 (10324617)
• Project Period (FY): 2014-07-18 – 2017-03-31
• Keywords: 数理モデル / 植物細胞壁 / 葉表皮細胞 / 形態形成 / 座屈 / シロイヌナズナ / 反応拡散

Outline of Final Research Achievements

We investigated the mechanism of the formation of the jigsaw puzzle-like morphology in pavement cells in dicotyledonous plants by using a mathematical model. We developed the mathematical model that considers the balance between cell and cell wall growth, restricted global cell growth orientation, and regulation of local cell outgrowth mediated by a Rho-like GTPase-cytoskeleton system. Our computational simulations suggest that interdigitated patterns form because of mechanical buckling in the absence of Rho-like GTPase-dependent regulation of local cell outgrowth. Our model clarifies the cell wall mechanics influencing pavement cell morphogenesis.

Free Research Field

数理生物学、発生生物学