To elucidate the mechanism of bone and cartilage disease in growth phase

2015 Fiscal Year Final Research Report

• Project/Area Number: 26560279
• Research Category: Grant-in-Aid for Challenging Exploratory Research
• Allocation Type: Multi-year Fund
• Research Field: Rehabilitation science/Welfare engineering
• Research Institution: Saitama Prefectural University
• Principal Investigator: Kokubun Takanori 埼玉県立大学, 保健医療福祉学部, 助教 (10616395)
• Co-Investigator(Kenkyū-buntansha): KANEMURA NAOHIKO 埼玉県立大学, 保健医療福祉学部, 教授 (20379895) ; SHIROGANE SATOSHI 国立障害者リハビリテーションセンター(研究所), 福祉機器臨床評価研究室, 室長 (90404764)
• Project Period (FY): 2014-04-01 – 2016-03-31
• Keywords: エンテーシス / メカニカルストレス / モーメント / 成長期骨軟骨疾患

Outline of Final Research Achievements

In this study, The group of eccentric contraction with down-hill running indicated an increase of calcified fibrocartilage zone compared to other exercise groups in animal experiment. These results suggested the factors of bone and cartilage disease in growth phase were affected by specificity of mechanical stress not primitive overuse.
From the biomechanical studies, although increasing of the knee moment affected by trunk alignment, muscle activities were not changed in lineary. These results suggested that the inconsistency of mechanical stress and muscle activities related to the mechanism of bone-cartilage disease in growth phase. Our results explained eccentric contraction may induce the inflammation of bone insertion site.

Free Research Field

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