Effects of hypoxia on skeletal muscle hypertrophy

2017 Fiscal Year Final Research Report

• Project/Area Number: 26560353
• Research Category: Grant-in-Aid for Challenging Exploratory Research
• Allocation Type: Multi-year Fund
• Research Field: Sports science
• Research Institution: National Institute of Fitness and Sports in Kanoya
• Principal Investigator: MIYAMOTO NAOKAZU 鹿屋体育大学, スポーツ生命科学系, 准教授 (20420408)
• Co-Investigator(Kenkyū-buntansha): 橋本 健志 立命館大学, スポーツ健康科学部, 教授 (70511608)
• Project Period (FY): 2014-04-01 – 2018-03-31
• Keywords: 低酸素 / 筋肥大 / 骨格筋

Outline of Final Research Achievements

We first examined how exposure of skeletal muscle cells to hypoxic environment affects muscle differentiation (Study 1). In Study 2, based on the results of Study 1, we examined the usefulness of resistance training under hypoxic environment to muscle hypertrophy in human in vivo. In Study 1, muscle differentiation was delayed or inhibited under a severe hypoxic condition, whereas hypertrophy of skeletal muscle fibers was observed under a mild hypoxic condition. In Study 2, resistance training load (load and repetition) was not changed in an appropriate hypoxic condition.

Free Research Field

トレーニング科学