New methods to induce skeletal muscle hypertrophy using reactive oxygen species

2016 Fiscal Year Final Research Report

• Project/Area Number: 26560375
• Research Category: Grant-in-Aid for Challenging Exploratory Research
• Allocation Type: Multi-year Fund
• Research Field: Sports science
• Research Institution: 防衛大学校(総合教育学群、人文社会科学群、応用科学群、電気情報学群及びシステム工学群) (2015-2016); Ritsumeikan University (2014)
• Principal Investigator: Makanae Yuhei 防衛大学校(総合教育学群、人文社会科学群、応用科学群、電気情報学群及びシステム工, 総合教育学群, 助教 (00706632)
• Co-Investigator(Renkei-kenkyūsha): Fujita Satoshi 立命館大学, スポーツ健康科学部, 教授 (80451863) ; Nakazato Koichi 日本体育大学, 保健医療学部, 教授 (00307993) ; Sato Koji 神戸大学, 人間発達環境学研究科, 准教授 (20584022) ; Ogasawara Riki 名古屋工業大学, 工学系研究科, 准教授 (10634602)
• Project Period (FY): 2014-04-01 – 2017-03-31
• Keywords: 運動 / 骨格筋 / mTORC1 / 活性酸素種 / レジスタンス運動

Outline of Final Research Achievements

The purpose of this study was to investigate the effects of reactive oxygen species (ROS) injection and the combination of ROS injection and resistance exercise on the mTORC1 activity. The exogenous increase in ROS stimulated mTORC1 activity at basal state. However, it did not further stimulate resistance exercise-induced mTORC1 activation.

Free Research Field

運動生理学