2015 Fiscal Year Final Research Report
Identification of glycogen sensor in the liver
Project/Area Number |
26560392
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Research Category |
Grant-in-Aid for Challenging Exploratory Research
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Allocation Type | Multi-year Fund |
Research Field |
Applied health science
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Research Institution | University of Tsukuba |
Principal Investigator |
Yahagi Naoya 筑波大学, 医学医療系, 准教授 (60420246)
|
Project Period (FY) |
2014-04-01 – 2016-03-31
|
Keywords | エネルギー代謝 / 栄養 |
Outline of Final Research Achievements |
We recently found that glycogen shortage during fasting triggers liver-brain-adipose neurocircuitry to facilitate fat utilization (Nature Commun. 2013). In the current study, we tried to identify the glycogen sensor in the liver. Through transcriptome analyses, we found several candidate genes of these glycogen sensors.
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Free Research Field |
代謝学、栄養学、分子生物学
|