2015 Fiscal Year Final Research Report
In vivo PET brain connection imaging
Project/Area Number |
26560471
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Research Category |
Grant-in-Aid for Challenging Exploratory Research
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Allocation Type | Multi-year Fund |
Research Field |
Brain biometrics
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Research Institution | National Center of Neurology and Psychiatry |
Principal Investigator |
Ichinohe Noritaka 国立研究開発法人国立精神・神経医療研究センター, 神経研究所 微細構造研究部, 部長 (00250598)
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Project Period (FY) |
2014-04-01 – 2016-03-31
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Keywords | 生体内繊維連絡 / PET |
Outline of Final Research Achievements |
We have attached PET visible ligand with anterograde- and retrograde tracer, cholera-toxin-beta-subunit (CTB). This methods will be important to simultaneous recording from areas directly connected, and align diffusion tensor imaging with real connection. We have examined how far CTB moved during four hours. We found that CTB could move contralateral cortical areas. We have developed to bind CTB and ligand. We have tested various condition for this methods. For example, we have injected PET tracers on other's intention, and found not only prefrontal surface areas, but also cingulate cortex. Both are related to sympathy and empathy. We will plan to simultaneous recording from these two areas for examining computational style from recognition to sympathy.
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Free Research Field |
神経動物行動学
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