2015 Fiscal Year Final Research Report
The association among pre-term infants' DNA polymorphism/methylation, attachment formation and later outcomes
| Project/Area Number |
26590152
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| Research Category |
Grant-in-Aid for Challenging Exploratory Research
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| Allocation Type | Multi-year Fund |
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| Research Field |
Educational psychology
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| Research Institution | Tsurumi Junior College |
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Principal Investigator |
SAITO Akira 鶴見大学短期大学部, 保育科, 准教授 (10225691)
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| Project Period (FY) |
2014-04-01 – 2016-03-31
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| Keywords | アタッチメント / DNA多型・メチル化 |
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| Outline of Final Research Achievements |
Neither DRD4/5-HTTLPR polymorphism nor DRD4/SLC6A4 methylation ratio were not associated with gestational age. Multiple regression analysis yielded no association between dependent variables (i.e. NBAS, maternal sensitivity, DRD4/5-HTTLPR polymorphism, DRD4/SLC6A4 methylation ratio) and an independent variable (i.e. disorganized/disoriented score).
Mann-Whitney U test revealed the highest disorganized/disoriented score group against the lowest one showed significantly higher methylation ratio at certain SLC6A4 CpG sites.
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| Free Research Field |
発達心理学
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