Neural mechanisms of retrieval-induced forgetting in rats

2015 Fiscal Year Final Research Report

• Project/Area Number: 26590174
• Research Category: Grant-in-Aid for Challenging Exploratory Research
• Allocation Type: Multi-year Fund
• Research Field: Experimental psychology
• Research Institution: University of Tsukuba
• Principal Investigator: ICHITANI Yukio 筑波大学, 人間系, 教授 (80176289)
• Co-Investigator(Kenkyū-buntansha): YAMADA Kazuo 筑波大学, 人間系, 准教授 (30282312)
• Project Period (FY): 2014-04-01 – 2016-03-31
• Keywords: 検索誘導性忘却 / 自発的物体再認 / ラット / グルタミン酸NMDA受容体 / アセチルコリン受容体

Outline of Final Research Achievements

The act of remembering can cause forgetting. Successful retrieval not only facilitates later recall of the retrieved items, but also impairs later recall of the related or competing items in memory. This memory phenomenon has been demonstrated with the retrieval-practice paradigm introduced by Anderson et al. (1994). In this study, we demonstrated the “retrieval-induced forgetting” phenomenon in a spontaneous object recognition test in rats. Additionally, administration of drugs which have detrimental effects on memory retrieval diminished the phenomenon.

Free Research Field

実験心理学・行動神経科学