Development of digital counting method using SERS

2016 Fiscal Year Final Research Report

• Project/Area Number: 26600117
• Research Category: Grant-in-Aid for Challenging Exploratory Research
• Allocation Type: Multi-year Fund
• Research Field: Optical engineering, Photon science
• Research Institution: Osaka University
• Principal Investigator: Ando Jun 大阪大学, 工学研究科, 特任研究員(常勤) (40623369)
• Project Period (FY): 2014-04-01 – 2017-03-31
• Keywords: 表面増強ラマン散乱 / ラマン分光法

Outline of Final Research Achievements

Surface-enhanced Raman scattering spectroscopy uses metallic nanostructures, which amplifies Raman scattering signal from the molecule existing near the metal surface. Since it can identify molecular species of the sample at high sensitivity, and further provides information of the molecular structure and surrounding environment, it is expected to be a promising analytical method for various research fields. However, the range of its application has been limited, since the precise control of the degree of signal amplification is often challenging. In this research, digital counting was considered to use for the measure of the quantification of SERS signal, instead of the SERS signal intensity. By using it, improvement of the sensitivity of SERS measurement and quantitative analytical capability was examined.

Free Research Field

バイオフォトニクス