Hybridization Dynamics of Glucans with Polythiophene and Application to Sensing

2015 Fiscal Year Final Research Report

• Project/Area Number: 26620061
• Research Category: Grant-in-Aid for Challenging Exploratory Research
• Allocation Type: Multi-year Fund
• Research Field: Functional solid state chemistry
• Research Institution: Osaka University
• Principal Investigator: Fukuhara Gaku 大阪大学, 工学(系)研究科(研究院), 助教 (30505996)
• Project Period (FY): 2014-04-01 – 2016-03-31
• Keywords: 超分子化学 / アロステリズム / センシング

Outline of Final Research Achievements

The author has elucidated the mechanism of dynamic glucan-polythiophene hybridization by using curdlan and schizophyllan as representative unbranched and branched linear polysaccharides and polycationic PyPT as a chromophoric hybridization partner. The in situ hybridization to hetero-triplex [(Cur)2-PyPT] upon addition of an aqueous solution of PyPT to a DMSO solution of Cur at ambient temperatures turned out to be far from completion. It should be emphasized that polycationic PyPT can unzip Cur homo-triplex and hybridize with the resulting homo-duplex in neutral aqueous solutions, despite that Cur homo-triplex does not show any sign of disassembling even at high temperatures in the absence of PyPT or in the presence of neutral PT. Interestingly, the hetero-triplex disassembles to hetero-duplex at very high pHs (>11) through further deprotonation from Cur in the hetero-triplex.

Free Research Field

高分子化学