Development of chiral metal nanoparticle catalysts using biomass as support aiming carbon neutral

2015 Fiscal Year Final Research Report

• Project/Area Number: 26620076
• Research Category: Grant-in-Aid for Challenging Exploratory Research
• Allocation Type: Multi-year Fund
• Research Field: Synthetic chemistry
• Research Institution: The University of Tokyo
• Principal Investigator: Miyamura Hiroyuki 東京大学, 理学(系)研究科(研究院), 助教 (00548943)
• Project Period (FY): 2014-04-01 – 2016-03-31
• Keywords: セルロース / ロジウム / 金属ナノ粒子 / 不均一系触媒 / １，４付加反応 / 不斉合成 / 環境調和型触媒 / 固相NMR

Outline of Final Research Achievements

Cellulose-supported chiral Rh nanoparticle (NP) catalysts have been developed. The Rh NPs, which were well dispersed on cellulose, catalyzed the asymmetric 1,4-addition of arylboronic acids to enones and enoates, one of representative asymmetric carbon-carbon bond-forming reactions, in the presence of chiral diene ligands, providing the corresponding adducts in high yields with outstanding enantioselectivities without metal leaching. The solid state NMR analysis of chiral NP system directly suggested interactions between the Rh NPs and the chiral ligand on the cellulose. This is the first example of polysaccharide-supported chiral metal nanoparticles for asymmetric carbon-carbon bond-forming reactions.

Free Research Field

有機化学