2015 Fiscal Year Final Research Report
Regioselective activation of C-H bond using newly-designed metal complexes
| Project/Area Number |
26620077
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| Research Category |
Grant-in-Aid for Challenging Exploratory Research
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| Allocation Type | Multi-year Fund |
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| Research Field |
Synthetic chemistry
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| Research Institution | Gakushuin University |
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Principal Investigator |
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| Project Period (FY) |
2014-04-01 – 2016-03-31
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| Keywords | C-H結合 / カルベン |
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| Outline of Final Research Achievements |
In this research, two types of C-H bond functionalization methodologies were explored.
The first one was the exploration of a new catalyst bearing a substrate capturing site for regioselective C-H bond activation. And it was found that newly-designed iridium-phenanthroline complex promoted meta-selective C-H borylation of mono-substituted benzenes, albeit chemical yields were not satisfactory.
The second approach was the utilization of photochemical isomerization of acylsilanes to siloxycarbenes for C-H insertion reaction and stereoselective cyclization of ortho-substituted benzoylsilanes was realized under photoirradiation conditions.
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| Free Research Field |
有機合成化学
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