Synthesis of polypeptide by alternating copolymerization of imines with carbon monoxide

2016 Fiscal Year Final Research Report

• Project/Area Number: 26620093
• Research Category: Grant-in-Aid for Challenging Exploratory Research
• Allocation Type: Multi-year Fund
• Research Field: Polymer chemistry
• Research Institution: Tokyo Institute of Technology
• Principal Investigator: Takeuchi Daisuke 東京工業大学, 科学技術創成研究院, 准教授 (90311662)
• Project Period (FY): 2014-04-01 – 2017-03-31
• Keywords: 触媒 / ペプチド / 共重合 / 一酸化炭素 / ポリアミド / ブタジエン

Outline of Final Research Achievements

Synthesis of polypeptides by alternating copolymerization of imines with carbon monoxide was investigated. The reaction of phenylaldimine with carbon monoxide by mononuclear Pd complex resulted in almost no polymerization. The reaction of cinnamaldimine or cyclobutanimie with carbon monoxide afforded insoluble product or oligomeric product. Dinuclear Pd complexes and aluminum-palladium complexes were designed and utilized for the reaction, but almost no polymerization took place. Aluminum-cobalt and aluminum-nickel complexes were found to show higher catalytic activity toward the polymerization of butadiene than the corresponding mononuclear cobalt and nickel complexes.

Free Research Field

高分子合成