Single electron tunneling in lipid bilayers as a novel sensing principle

2015 Fiscal Year Final Research Report

• Project/Area Number: 26620111
• Research Category: Grant-in-Aid for Challenging Exploratory Research
• Allocation Type: Multi-year Fund
• Research Field: Analytical chemistry
• Research Institution: Tohoku University
• Principal Investigator: Hirano-Iwata Ayumi 東北大学, 医工学研究科, 准教授 (80339241)
• Co-Investigator(Kenkyū-buntansha): NIWANO MICHIO 東北大学, 電気通信研究所, 教授 (20134075) ; KIMURA YASUO 東北大学, 電気通信研究所, 准教授 (40312673) ; YAMAMOTO HIDEAKI 東北大学, 学際科学フロンティア研究所, 助教 (10552036)
• Project Period (FY): 2014-04-01 – 2016-03-31
• Keywords: 脂質二分子膜 / 単電子トンネリング / ナノデバイス / 単電子トランジスタ

Outline of Final Research Achievements

This study aims at realization of single-electron tunneling in lipid bilayers as a new sensing principle. We first examined incorporation of nanoparticles into lipid bilayers and found that only very small nanoparticles could be incorporated into self-standing bilayer lipid membranes. We next examined simulation on single-electron effects of aligned nanoparticles and revealed that observable single-electron effects would be possible even at room temperature. In addition, we have established fabrication procedures for silicon chips with wired metal electrodes. We would like to combine these techniques to realize single-electron tunneling in lipid bilayers and apply to highly sensitive biosensors to demonstrate a novel sensing principle.

Free Research Field

分析化学