Development of single-molecule reactors for single-molecule regulated chemistry

2015 Fiscal Year Final Research Report

• Project/Area Number: 26630403
• Research Category: Grant-in-Aid for Challenging Exploratory Research
• Allocation Type: Multi-year Fund
• Research Field: Reaction engineering/Process system
• Research Institution: Osaka Prefecture University
• Principal Investigator: Xu Yan 大阪府立大学, 21世紀科学研究機構, 講師 (90593898)
• Project Period (FY): 2014-04-01 – 2016-03-31
• Keywords: アトリットル液滴 / ナノ流体デバイス / Nano-in-Nano集積化 / １分子制御化学

Outline of Final Research Achievements

In this study, toward the realization of single-molecule regulated chemistry which is a new concept proposed by us, a method for the formation of attoliter droplets using a nanofluidic device was developed. The high-precision fabrication of local hydrophilic/hydrophobic nanopatterns in tiny nanofluidic channels, which are the core structures proposed by us for the formation of attoliter droplets, was achieved by using a nano-in-nano integration technology developed by us. The liquid-handling experimental results revealed that the fabricated nanofluidic device containing the high-precision hydrophilic/hydrophobic nanopatterns possessed the capability to form attoliter droplets based on the principle of Laplace pressure difference at the liquid/gas interface in the nanofluidic channel.

Free Research Field

ナノ化学システム、１分子科学