2015 Fiscal Year Final Research Report
Functional analyses of the role of oncomodulin in axon regeneration
| Project/Area Number |
26640048
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| Research Category |
Grant-in-Aid for Challenging Exploratory Research
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| Allocation Type | Multi-year Fund |
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| Research Field |
Neurochemistry/Neuropharmacology
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| Research Institution | Tokyo Metropolitan Institute of Medical Science |
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Principal Investigator |
HARADA Takayuki 公益財団法人東京都医学総合研究所, 運動・感覚システム研究分野, 分野長 (90345306)
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| Project Period (FY) |
2014-04-01 – 2016-03-31
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| Keywords | 軸索再生 / Oncomodulin |
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| Outline of Final Research Achievements |
We tried to identify the receptor for oncomodulin and found several possible molecules. Overexpression of some of these molecules enhanced oncomodulin-mediated axon regeneration of retinal ganglion cells in vitro. We will continue to analyze other molecules and elucidate in detail the molecular pathways for oncomodulin.
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| Free Research Field |
神経科学
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