Survey for immunologic suppressor factors encoded in the intracellular parasitic bacterial genome

2015 Fiscal Year Final Research Report

• Project/Area Number: 26640111
• Research Category: Grant-in-Aid for Challenging Exploratory Research
• Allocation Type: Multi-year Fund
• Research Field: Genome biology
• Research Institution: Hosei University
• Principal Investigator: OSHIMA Kenro 法政大学, 生命科学部, 教授 (00401183)
• Project Period (FY): 2014-04-01 – 2016-03-31
• Keywords: ゲノム / 寄生 / ファイトプラズマ

Outline of Final Research Achievements

Phytoplasmas are intracellular bacterial pathogens of plants and insects and cause devastating yield losses in diverse low- and high-value crops worldwide. To investigate the molecular mechanisms of the regulation of the host cells, we focused on phytoplasma-secreted proteins. As a result of screening, we found a phytoplasma-secreted protein, PHYL1, which induces morphological changes in flowers that are similar to those seen in phytoplasma-infected plants. By yeast two-hybrid and in planta transient coexpression assays, we found that PHYL1 interacts with and degrades floral homeotic MADS-domain proteins.

Free Research Field

植物病理学