2015 Fiscal Year Final Research Report
Investigation whether gap junction works wildly for skin pattern formation
| Project/Area Number |
26650078
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| Research Category |
Grant-in-Aid for Challenging Exploratory Research
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| Allocation Type | Multi-year Fund |
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| Research Field |
Developmental biology
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| Research Institution | Osaka University |
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Principal Investigator |
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| Project Period (FY) |
2014-04-01 – 2016-03-31
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| Keywords | パターン形成 / ゼブラフィッシュ / 体表模様 / ギャップジャンクション |
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| Outline of Final Research Achievements |
In the morphogenesis of organisms, we observe autonomous pattern formation based on the Reaction-Diffusion (R-D) model (Turing). We have reported that zebrafish skin pattern formation is based on the R-D model and aim to disclose the molecular mechanism in this pattern formation. We also have reported that gap junction is one of the most important factor for cell-cell interaction among pigment cells. In this study we analyzed gap junction genes of teleosts species including zebrafish. We found that connexin genes that are involved in skin pattern formation are highly conserved among teleosts and that they may function for Turing pattern formation.
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| Free Research Field |
発生生物学
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