2016 Fiscal Year Final Research Report
Development of transcriptional study using new transcriptional repression motif ERD
| Project/Area Number |
26650101
|
|---|
| Research Category |
Grant-in-Aid for Challenging Exploratory Research
|
| Allocation Type | Multi-year Fund |
|---|
| Research Field |
Plant molecular biology/Plant physiology
|
|---|
| Research Institution | Hiroshima University |
|---|
Principal Investigator |
|
|---|
| Project Period (FY) |
2014-04-01 – 2017-03-31
|
| Keywords | 植物 / 発現制御 |
|---|
| Outline of Final Research Achievements |
Plant MYB transcription factor EPR1 can repress transcription in yeasts and animal cells as well as in plant cells. In this study, we aim to identify the transcriptional repression motifs of EPR1 in plants, yeasts, and animals, respectively and clarify the molecular mechanisms of transcriptional repression conserved in eukaryotes. Our analysis showed that EPR1 has two transcriptional repression motifs. The domain D in the C-terminal region cannot suppress the transcriptional activity in animal cells, while domain A in the N-terminal region suppress the transcriptional activity in plants, yeasts, and animal cells. Transcriptional repression of EPR1 across kingdoms might depend on two independent motifs with different mechanisms.
|
| Free Research Field |
植物生理・分子
|
