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2015 Fiscal Year Final Research Report

A milk peptide fraction for preventing the allergies and autoimmune diseases

Research Project

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Project/Area Number 26660105
Research Category

Grant-in-Aid for Challenging Exploratory Research

Allocation TypeMulti-year Fund
Research Field Food science
Research InstitutionGunma University

Principal Investigator

ENOMOTO Atsushi  群馬大学, 大学院理工学府, 准教授 (70183217)

Project Period (FY) 2014-04-01 – 2016-03-31
Keywordsミルク / ペプチド / T細胞 / 1型糖尿病 / 慢性関節リウマチ / 自己免疫疾患 / 鶏卵アレルギー / 免疫抑制剤
Outline of Final Research Achievements

A milk peptide fraction (MPF) newly purified from cow’s milk was found to directly act on T cells of BALB/c, NOD and OVA-IgE mice, and to highly inhibit their proliferative responses and cytokine responses. In addition, MPF was also shown to suppress the onset of Type 1 diabetes of NOD mice. Our findings may be useful for preventing the allergies and autoimmune diseases.

Free Research Field

食品免疫学

URL: 

Published: 2017-05-10   Modified: 2020-03-30  

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