2015 Fiscal Year Final Research Report
A milk peptide fraction for preventing the allergies and autoimmune diseases
| Project/Area Number |
26660105
|
|---|
| Research Category |
Grant-in-Aid for Challenging Exploratory Research
|
| Allocation Type | Multi-year Fund |
|---|
| Research Field |
Food science
|
|---|
| Research Institution | Gunma University |
|---|
Principal Investigator |
|
|---|
| Project Period (FY) |
2014-04-01 – 2016-03-31
|
| Keywords | ミルク / ペプチド / T細胞 / １型糖尿病 / 慢性関節リウマチ / 自己免疫疾患 / 鶏卵アレルギー / 免疫抑制剤 |
|---|
| Outline of Final Research Achievements |
A milk peptide fraction (MPF) newly purified from cow’s milk was found to directly act on T cells of BALB/c, NOD and OVA-IgE mice, and to highly inhibit their proliferative responses and cytokine responses. In addition, MPF was also shown to suppress the onset of Type 1 diabetes of NOD mice. Our findings may be useful for preventing the allergies and autoimmune diseases.
|
| Free Research Field |
食品免疫学
|
