2016 Fiscal Year Final Research Report
Why the ipsilateral relationship where first follicular wave dominant follicle and corpus luteum are present in the same ovary decrease fertility in cattle?
| Project/Area Number |
26660234
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| Research Category |
Grant-in-Aid for Challenging Exploratory Research
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| Allocation Type | Multi-year Fund |
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| Research Field |
Veterinary medical science
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| Research Institution | Obihiro University of Agriculture and Veterinary Medicine |
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Principal Investigator |
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| Project Period (FY) |
2014-04-01 – 2017-03-31
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| Keywords | 卵巣 / 黄体 / 卵胞 / 受胎性 / 乳牛 |
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| Outline of Final Research Achievements |
The effects of the locational relationship between the first follicular wave dominant follicle (W1DF) and the corpus luteum (CL) on fertility after insemination were examined in dairy cattle. In the ipsilateral relationship where W1DF and CL are present in the same ovary, the conception rate was significantly lower than that in the contralateral relationship where W1DF and CL are exist in different ovaries. In the contralateral relationship, the concentration of progesterone (P4) in the blood and endometrial tissues at the early stage after ovulation was higher, and the mRNA expression of P4 receptor (PGRMC2) was higher in the ipsilateral relationship. Therefore, the positional relationship between W1DF and CL may regulate P4 concentration and expression of P4 receptor in the endometrium, and then affect fertility. Since hormonal treatments changed the positional relationship between W1DF and CL, the positional relationship might be regulated artificially.
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| Free Research Field |
獣医臨床繁殖学
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