2015 Fiscal Year Final Research Report
Establishment of the strategy to purify transcription regulatory complex using immobilized DNA template
| Project/Area Number |
26670130
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| Research Category |
Grant-in-Aid for Challenging Exploratory Research
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| Allocation Type | Multi-year Fund |
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| Research Field |
General medical chemistry
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| Research Institution | Hokkaido University |
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Principal Investigator |
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| Project Period (FY) |
2014-04-01 – 2016-03-31
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| Keywords | 転写制御 |
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| Outline of Final Research Achievements |
We performed the purification of transcription regulatory factors using immobilized promoter DNA template. We perform Mass spectromic analysis to
identify transcription regulatory factors. We took advantage of the method and found that novel transcription elongation complex called "little elongation complex (LEC)" is recruited to the snRNA gene promoters by Mediator complex.
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| Free Research Field |
遺伝子発現制御
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