2015 Fiscal Year Final Research Report
Identification of HCN4-expressing neurons using HCN4-luciferase knock-in mouse
| Project/Area Number |
26670292
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| Research Category |
Grant-in-Aid for Challenging Exploratory Research
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| Allocation Type | Multi-year Fund |
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| Research Field |
Pain science
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| Research Institution | Kurume University |
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Principal Investigator |
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| Co-Investigator(Renkei-kenkyūsha) |
NAKASHIMA Noriyuki 久留米大学, 医学部, 助教 (80625468)
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| Project Period (FY) |
2014-04-01 – 2016-03-31
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| Keywords | HCN4 / ニューロン / 脊髄後角 / 大脳皮質 |
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| Outline of Final Research Achievements |
We generated transgenic mouse, in which cDNA of firefly luciferase-GFP fusion protein was knocked in at HCN4 locus (HCN4+/Luc), and visualized HCN4-expressing neurons in central nervous system. HCN4-expressing neurons were found in dorsal horn of spinal cord, and in III layer of sensory cortex.
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| Free Research Field |
生理学
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