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2015 Fiscal Year Final Research Report

Research for optimization of bolus shape for carbon-ion therapy

Research Project

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Project/Area Number 26670298
Research Category

Grant-in-Aid for Challenging Exploratory Research

Allocation TypeMulti-year Fund
Research Field Medical Physics and Radiological Technology
Research InstitutionUniversity of Tsukuba

Principal Investigator

Takada Yoshihisa  筑波大学, 数理物質系, 教授 (00134205)

Project Period (FY) 2014-04-01 – 2016-03-31
Keywordsbolusの自動最適化設計 / single-material bolus / bi-material bolus / 炭素イオン線治療
Outline of Final Research Achievements

A range-compensating bolus is a key device to conform the irradiation field to the target boundary in carbon-ion therapy. We have developed a novel automated design method of the bolus by putting subscription doses in and around the target and OARs(Organs At Risk) and obtaining a bolus shape giving the optimum dose distribution by use of the least-square method. We have improved dose distribution in and around the target and OARs using the method. We have shown that dose in the OAR can be decreased significantly while keeping the dose uniformity in the target by using the bolus designed by the method.

Free Research Field

医歯薬学

URL: 

Published: 2017-05-10  

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