Development of a high sensitive and systematic analytical method of neonicotinoid insecticides in dietary intake which can utilize for exposure assessment

2016 Fiscal Year Final Research Report

• Project/Area Number: 26670343
• Research Category: Grant-in-Aid for Challenging Exploratory Research
• Allocation Type: Multi-year Fund
• Research Field: Hygiene and public health
• Research Institution: Aichi Prefectural Institute of Public Health
• Principal Investigator: WATANABE MINAE 愛知県衛生研究所, 衛生化学部医薬食品研究室, 主任研究員 (90525768)
• Co-Investigator(Renkei-kenkyūsha): UEYAMA Jun 名古屋大学, 大学院医学系研究科, 准教授 (00397465)
• Research Collaborator: SAITO Isao
• Project Period (FY): 2014-04-01 – 2017-03-31
• Keywords: 食品衛生 / ネオニコチノイド系殺虫剤 / 食品分析 / 食事

Outline of Final Research Achievements

Neonicotinoid insecticides (NEO) are one of the chemicals that are connected with the daily life closely, and widely used for daily necessities as well as agriculture. The daily exposure through the meal is concerned about adversely affect hearth caused by the characteristic property. Therefore, we studied the high sensitive analytical method of NEO which can utilize for exposure assessment. As a result, pre-freezing and cryogenic milling with powdered dry ice adopted of the method of crushing, and the obtained sample was homogenized with acetic acid aqueous solution, and extracted with n-hexane and acetonitrile. Co-extractives were clean up with GPC and SAX/PSA mini-column solid-phase extraction (SPE). The prepared sample solution was measured using LC-MS/MS.

Free Research Field

医歯薬学