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2015 Fiscal Year Final Research Report

Disease modeling for SCVTdP by iPS cells

Research Project

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Project/Area Number 26670408
Research Category

Grant-in-Aid for Challenging Exploratory Research

Allocation TypeMulti-year Fund
Research Field Cardiovascular medicine
Research InstitutionKeio University

Principal Investigator

Yuasa Shinsuke  慶應義塾大学, 医学部, 講師 (90398628)

Project Period (FY) 2014-04-01 – 2016-03-31
KeywordsiPS細胞 / 心筋細胞 / 不整脈
Outline of Final Research Achievements

We generated iPS cells from patients with short coupled variant TdP (SCVTdP). Cardiomyocytes were differentated from control-iPS cells and SCVTdP-iPS cells. Then we performed the electrophysiological analysis using iPS cell-derived cardiomyocytes. We identified the specific phenotype in SCVTdP-iPS cell-derived cardiomyocytes.

Free Research Field

循環器内科

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Published: 2017-05-10  

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